As stacks get deeper and deeper, you should change and adjust your strategy. There are three main, high-level reasons for this.
First of all, the position becomes increasingly important. With deeper stacks, equity realization shifts significantly more toward the in-position player. In the simplest of terms, the player in position gets much more control over when they want or do not want to play a big pot.
Secondly, when playing deep, the nut advantage will have a bigger influence on your overall strategy. If you make the nuts, you can play for a lot of money. Simultaneously, the ability to make the nuts on different turns and rivers goes up in value.